Violence / Gore: Koto (and her brothers to a degree) is rather violent and destructive, in one flashback she is shown beating up a kid in her school. There is a flashback involving a young boy committing suicide after the death of his parents (he does not succeed because of plot reasons) and both those events show blood. This flashback is shown more than once.

Nudity / Sexual Content: A bit of fanservice. Danji walks around in her apartment in her underwear and it's implied she and Myoue are sleeping together.

Theological Themes: The theology/mythology of the show is rather complex. For starters youkai exist in the Mirror Capital, there are monks and priests, a character has the power to make the things he draws come alive, one non-human character gets a human body from a bodhisattva and there are parallel worlds/planes of existence. There are very definite gods (as characters who interact with other characters) revealed later in the show, who are creators and overseers of reality. If any of this sounds vague it's because I'm trying to avoid spoilers and because some of it was confusing and needs to be re-watched.

Negative Themes: Some minor swear words.